Qualitative and quantitative analysis of the cellular response in sterile acute inflammation

ABSTRACT

A study of the cellular response in acute inflammation produced by the intraperitoneal injection of sterile egg-albumin in adult male rabbits was carried out over a time interval of 06, 24 and 72 hours. The early response was stereotyped phenomenon and was accompanied by an increase in, polymorphs [P < 0.01] which completely disappeared at 24 hours. In the late hours gradual increase in mesothelial cells was noted which reached highest levels at 72 hours [P < 0.01]. The levels of lymphocytes started rising in the exudate [P < 0.05] at 72 hours. The eggalbumin caused a marked response of mesothelial cells in the peritoneal cavity, when the initial response of polymorphs was over