Abdominal wound closure: a prospective randomized trial of polypropylene and polydioxanone

ABSTRACT

Results of a prospective study on 164 patients, comparing the polydioxanone [PDS[R]] and polypropylene [Prolene [R]] in laparotomy wound closure; over a 30 month period are presented. All types of laparotomy wounds were considered for evaluation. Patients were analyzed for early and late wound related complications. Overall wound infection was 11%. Whereas no significant difference between two sutures was noticed for the early postoperative complications, persistent wound pain, palpable knots, and suture sinuses were significantly less with less with PDS in continued follow up [mean 24.5 months]. With the comparable safety in early postoperative period and significantly lower incidence of delayed complications, PDS can be regarded as near-to-ideal suture material for closing all types of laparotomy wounds