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Effect of diazinon and / or praziquantel on selected protein aspects in healthy and Schistosoma mansoni infected mice
Journal of the Egyptian Society of Parasitology. 2003; 33 (1): 145-62
em Inglês | IMEMR | ID: emr-62832
ABSTRACT
The effect of 1/20 LD50 diazinon given orally to healthy and Schistosomiasis mansoni infected mice for 5-9 successive days and 17 weeks coupled with a therapeutic dose [2x500 mg/kg b. Wt.] of praziquantel two weeks before sacrificing. The results showed insignificant differences obtained from total proteins, albumin, globulins and albumin/globulin ratio. However, significant differences were revealed from alpha 1, alpha 2, beta 1, beta 2 and gamma-globulins in addition to plasma ceruloplasmin. Diazinon changed the levels of alpha 2, beta 1 and gamma-globulins, while diazinon coupled with schistosomiasis affected the levels of most of the studies parameters
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Praziquantel / Schistosoma mansoni / Ceruloplasmina / Proteínas / Reativadores da Colinesterase / Diazinon / Albuminas / Combinação de Medicamentos / Camundongos Limite: Animais Idioma: Inglês Revista: J. Egypt. Soc. Parasitol. Ano de publicação: 2003

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Praziquantel / Schistosoma mansoni / Ceruloplasmina / Proteínas / Reativadores da Colinesterase / Diazinon / Albuminas / Combinação de Medicamentos / Camundongos Limite: Animais Idioma: Inglês Revista: J. Egypt. Soc. Parasitol. Ano de publicação: 2003