Vaccination trial against experimental trichinellosis using autoclaved trichinella spiralis larvae vaccine [ATSLV]
Journal of the Egyptian Society of Parasitology. 2003; 33 (1): 219-28
em Inglês
| IMEMR
| ID: emr-62837
ABSTRACT
The autoclaved Trichinella spiralis larvae vaccine [ATSLV] was tested and showed unpredictable effect on the immune system of mice experimentally infected with T. spiralis. The vaccine was given with Bacillus Calmette-Guerin [BCG] as an adjuvant at different durations and by different routes of administration. The best result was achieved by given the vaccine twice intradermally with two-week interval as evidenced by a significant reduction in adult and larval count, as well as reproductive capacity index. Histopathologically, there was a significant reduction in the number of the encysted larvae, which showed degeneration and hyalinization of the cyst wall accompanied by early pericystic fibrosis
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Vacina BCG
/
Imunoterapia Ativa
/
Larva
/
Camundongos
Limite:
Animais
Idioma:
Inglês
Revista:
J. Egypt. Soc. Parasitol.
Ano de publicação:
2003
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