Types of the endoneurial oedema after the crush injury of the peripheral nerve in albino rat

ABSTRACT

This study included 20 male albino rats; the left common peroneal nerves of 18 rats were subjected to crush injury, while 2 rats were used as a control. The common peroneal nerves were exposed and some of their parts distal to the crush injury were taken. The specimens were prepared for study by electron microscope. The results showed that the endoneurial edema was distributed all over the endoneurium, especially in the sub-perineurial and perivascular areas forming sub- perineurial and perivascular edema. The axoplasm of the nerve axons showed edema fluid causing a separation of its contents of the cell organelles, intra-axonal edema. Also, the mitochondria became swollen with ill-defined internal cristae, intra-mitochondrial edema. The endothelial cells of the endoneurial blood vessels became partially swollen due to internal edema. The perineurium also became thick and edematous due to the presence of fluid between its layers, intra-perineurial edema