Post surgical wound infections: a study on threats of emerging resistance

ABSTRACT

300 bacterial isolates associated with post surgical wound infections were tested in vitro for their sensitivity/resistance pattern against 20 antibacterial agents. The study indicated that the bacteria in which clinically significant resistance has now become a potential problem include Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Proteus. Klebsiella, Staphylococcus epidermidis, Enterobacter and Citrobacter species. Among the tested drugs the percent resistance rate observed were tobramycin [9.75%], amikacin [10.03%], enoxacin [20.53%], ofloxacin [25.93%], ciprofloxacin [26.27%], gentamicin [29.03%], ceftrioxone [36%], aztreonam [41.07%], cefaclor [44.07%]. The conclusion from the study can be drawn that tobramycin and amikacin [aminoglycosides] and enoxacin, ciprofloxacin and ofloxacin [Fluoroquinolones] are very effective agents for treating post surgical wound infections. However resistance to these agents is rapidly increasing