Comparison between single dose versus seven days metronidazole therapy in treatment of trichomonas vaginalis vaginitis

ABSTRACT

Comparison between single dose use of metronidazole versus seven days therapy in the treatment of trichomonas vaginalis infection. Design and Setting: A one year study from September 2002 to August 2003 conducted at Ghurki Trust Teaching Hospital attached with Lahore Medical and Dental College, Lahore. The total number of patients included are 109. Main Outcome Measure: Comparative treatment results of single dose versus 7 days therapy of metronidazole in treatment of trichomonas vaginalis. 54 patients received metronidazole for 7 days. 51[94.44%] were free of infection. 3 did not respond to treatment and were retreated in the same way. 55 patients received 3 gm single dose treatment. 53% [96.36%] were free of infection while 3 patients required repeat treatment. Conclusions: Single dose treatment is an acceptable option with few side effects and better compliance