Hepatitis C virus infection at Sharkia Governorate, Egypt: Seroprevalence and associated risk factors
Journal of the Egyptian Society of Parasitology. 2004; 34 (1): 367-84
em Inglês
| IMEMR
| ID: emr-66734
ABSTRACT
A sample of 1422 individuals was included in the study, using multistage sampling technique. Exposures and demographic characteristics were obtained through a pre-designed questionnaire. Antibody to HCV was assessed using micro-particle enzyme immunoassay [MEIA] enzyme assay by IMX and the HCV RNA was tested by real-time PCR technique using ABI Prism 7700 system. The seroprevalence of antibodies to HCV was 23.4% and 27.4% in urban and rural areas, respectively, with an overall prevalence of 25.8%. This reflected prior HCV infection, but not necessarily a current liver disease. The prevalence was higher among males than females and increased sharply with age, from 4.8% in those <20 years old to 41.9% in the older ages [>/40 years]. Those who were not educated and farmers had a significantly high prevalence. The significant predictors of HCV infection were previous parenteral therapy for schistosomiasis [OR = 4.3, 95%, CI = 3.6-7.9], among those over 20 years of age [3.5, 2.18-5.8], blood transfusion [4.1, 2.4-6.9], invasive procedures [surgery and endoscopy] and the use of contaminated syringes and needles. Also, shaving at community barbers added a significance to the model
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
População Rural
/
População Urbana
/
Transfusão de Sangue
/
Esquistossomose mansoni
/
Testes Sorológicos
/
Reação em Cadeia da Polimerase
/
Prevalência
/
Fatores de Risco
/
Técnicas Imunoenzimáticas
/
Anticorpos Anti-Hepatite C
Tipo de estudo:
Estudo de prevalência
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
J. Egypt. Soc. Parasitol.
Ano de publicação:
2004
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