Journal of the Egyptian Society of Parasitology. 2004; 34 (1): 479-88
em Inglês
| IMEMR
| ID: emr-66741
ABSTRACT
In this study, the role of aflatoxin contamination in the onset of liver cancer in HCV-infected patients was studied. The quantitative identification of the possible aflatoxins contamination in six urban and eleven rural areas using high performance liquid chromatography technique revealed that corn, wheat, peanut, lupine "tennis", white rice, cowpea "lobiya", fava bean and brown rice showed a prevalence of AFB1 [64.7%, 53%, 53%, 47%, 47%, 41%, 29.4% and 29.4%, respectively]. A positive correlation was found between aflatoxin and positive HCV- PCR together with liver disease progression to G3S3, the indicative of hepatocellular carcinoma. Such correlation was not fully understood, but the oncogene amplification caused by HCV- infection may be aggravated by the consumption of aflatoxin contaminated raw food materials or their products
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
População Rural
/
População Urbana
/
Contaminação de Alimentos
/
Fatores de Risco
/
Cromatografia Líquida de Alta Pressão
/
Hepacivirus
/
Carcinoma Hepatocelular
/
Aflatoxinas
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
J. Egypt. Soc. Parasitol.
Ano de publicação:
2004
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