Investigation of Induced biochemical and histopathological parameters of acetonitril extract of Jatropha carcus in albino rats

ABSTRACT

Toxicological and histopathological investigations were carried on the acetonitrile extract from J. Carcus in comparison with praziquantel, the known anti-schistosomal drug. On a constant weight dose bases [single dose of 50 mg/kg body weight injected orally to albino rats], the acetonitrile extract from J. carcus showed mild toxicological parameters, biochemical parameters as well as histopathological profile in comparison with the control. However, these side effects were nonsignificant compared with the severe side effects caused by praziquantel