Diagnostic potentials of copro - antigen detection based Elisa compared to microsocopy in intestinal amoebiasis

ABSTRACT

This study was performed on 93 patients clinically presumed to have intestinal amoebiasis. Stool samples were collected from all of them and subjected to microscopic examination and Entamoeba coproantigens detection using Entamoeba and Entamoeba II tests. Out of 93 clinically positive samples, 51 were found positive by microscopy, while 49 were detected by Entamoeba test as having antigens specific for E. Histolytica/E. dispar [88.24% sensitivity]. Among 49 specimens, 4 were demonstrated as microscopy negative [90.48% specificity]. Entamoeba II test demonstrated 16 specimens having antigens specific for the pathogenic E. histolytica among 49 positive by Entamoeba test, while 33 were positive for nonpathogenic E. Dispar coproantigens