Pre-operative port sites infiltration and intraperitoneal administration of bupivacaine: Does it effectively reduce pain after laparoscopic cholecystectomy?

ABSTRACT

To examine the efficacy of preoperative port sites infiltration and /or intraperitoneal administration of bupivacaine in alleviating pain after laparoscopic cholecystectomy [LC], 80 patients scheduled for elective laparoscopic cholecystectomy were recruited. They were blindly r and omized to 4 groups, 20 patients each. Group A received bupivacaine infiltration in port sites before skin incision as well as intraperitoneal instillation, group B received bupivacaine in port sites only, group C received bupivacaine intraperitoneally only and group D served as a control group and had no treatment. Postoperative pain [viscer al and somatic] and nausea were studied at 1, 2, 3, 6, 9, 12, 24, 36 and 48 hours after operation. The study showed that the combination of preoperative port sites infiltration and intraperitoneal administration of bupivacaine significantly reduces postoperative nausea, port sites pain and shoulder tip pain, but does not affect headache or other types of pains after laparoscopic cholecystectomy