Homozygous severe protein C deficieny type I: Long-term prophylactic intermittent therapy with subcutaneous purified protein C concentrate: first case report from Kuwait

ABSTRACT

We describe here, with review of the relevant literature, our experience with subcutaneous protein C concentrate on a long-term basis for the prophylaxis of thrombotic episodes in a Kuwaiti girl with homozygous severe p rotein C deficiency - Type 1, causing neonatal purpura fulminans and blindness in left eye due to retinal vessel coagulopathy. To the best of our knowledge, this is the first such case report of this genetic disorder from Kuwait