Comparative study between epidural methylprednisolone and indomethacin in chronic low back pain patients using P300

ABSTRACT

Thirty patients were included in this study and divided into two equal groups Group I received 80 mg methylprednisolone [MTP] epidurally and group II received 2 mg lyophilized, preservative-free indomethacin [INM] epidurally. Another dose of the drug was given after two weeks. The values of absolute peak latencies and amplitudes of P300 were recorded before [baseline] and after two weeks of the first injection as well as after two weeks of the second injection in both groups. The intensity of pain was also recorded using a 10-cm visual analog scale [VAS]. The study concluded that INM administered epidurally is a good alternative to MTP whenever corticosteroids are contraindicated in chronic low back pain patients