Soft tissue reaction to bioactive glass composite blocks ossicular replacement prosthesis

ABSTRACT

Soft tissue reaction to bioactive glass composite ossicular replacement prosthesis has been evaluated in rabbits. One week after the implantation, mild inflammatory reaction was observed surrounding the prosthesis. This reaction was greatly reduced after one month and gradually replaced by a fibrous capsule without any foreign body giant cell, histiocyte or inflammatory cell infiltration. This encouraged using this material in human as ossicular replacement prosthesis with satisfactory results even without placement of a cartilage between the prosthesis and the fascia1 graft