Ropivacaine and hyaluronidase versus ropivacaine and lidocaine for peribulbar anaesthesia in cataract surgery with phacoemulsification

ABSTRACT

Comparison between the anaesthestic efficacy of 0.75% ropivacaine and 50UI/ ml hyaluronidase with 0.75% ropivacaine and 2% lidocaine during peribulbar anaesthesia for cataract surgery. The study is a double blind randomized clinical trial. Thirty physical status ASA asterisk I-Ill patients were randomly allocated to two groups. Ropivacaine/ hyaluronidase group received 5ml of 0.75% ropivacaine plus 50 IU ml[-1] hyalurnoidase [RH group], and ropivacaine/ lidocaine group received 5ml of equal parts of 0.75% ropivacaine and 2% lidocaine [RL group]. Speed of onset and quality of motor blockade were assessed using ocular and eyelid movement scores, and sensory blockade was assessed by the three- point scoring system. Surgical and patients satisfaction, and incidence of complications were recorded. The groups showed no difference in the rate of onset or degree of akinesis achieved. Akinesia scores of ropivacaine/ hyaluronidase mixture superior in peribulbar block. There were no differences between groups in patients satisfaction and in the incidence of minor complications. Ropivacaine 0.75% with hyaluronidase 50.IU ml[-1] quality of peribulbar block equivalent to ropivacaine 0.75% with lidocaine 29% However, it is superior as regards the need for supplementary anaesthesia