Effect of 50 Hz magnetic field with different intensities on some blood biochemical and hematological parameters

ABSTRACT

The present study has been undertaken to evaluate the biological changes that could be encountered in response to extremely low frequency [50 Hz] magnetic field with different intensities. The effect of magnetic field on oxidative stress [reduced glutathione [GSH] and total lipid peroxide [LPO]], hematological indices, total and differential leukocytes count, cardiac functions [creatinine phosphokinase [CPK] and lactate dehydrogenase [LDH]], level of calcium ions concentrations [Ca[++]] and total protein content have been investigated in this work. Sprague-Dawley rats were exposed to the magnetic field for two hours. The blood samples were collected before and after exposure. The level of serum total lipid peroxide showed a significant increase while the level of blood reduced glutathione content and hematological indices showed a significant decrease at the level of p<0.05 after exposure to magnetic field. The total leukocyte differentiation showed a small reduction but with no significance. The reduction in neutrophils obtained after exposure was significant. The decrease in the counts of lymphocytes, monocytes, eosinophils and basophils was not regular as the magnetic field changes. The work also records that creatinine phosphokinase [CPK] and lactate dehydrogenase [LDH] activities, the Level of serum calcium ion concentration [Ca[+2]] and serum total protein showed significant increases as a result of exposure to magnetic field