Synthesis of some new pyrazolones and benzimidazol-acetonitriles derived from xanthene

ABSTRACT

Alpha -cyano - [xanthen-9-yl]-hydrazides 2 were cyclised to give 3-amino-4 [substituted-xanthen-9-yl]-pyrazolo-5 [4H] ones 3. Benzimidazole -[9-xanthen] 2-acetonitrilss 7 were formed by condensation of benzimidazole jole-2-acetonitrile with xanthen-9-olea. 3 and 7 were pyrolysed under reduced pressure to give 9-substituted-xanthenes. Various classes of nitrogen hetegocydes such as benzimidazoles, pyrazolones and analogous hetegocydes have been previously prepared and investigated for their biological activities. The aim of this work is to synthesise such compounds in an attempt to obtain newer compounds of anticipated broad spectrum biological activities