Proliferative changes of epidermal cells in lesions of cutaneous leishamaniasis
Journal of the Egyptian Society of Parasitology. 2005; 35 (3): 761-772
em Inglês
| IMEMR
| ID: emr-72367
ABSTRACT
In 35 parasitologically proven zoonotic cutaneous leishmaniasis patients, the histopathological and immunohistochemical picture were studied. The haematoxylin and eosin stain, the monoclonal antibodies for T and B lymphocytes, peroxidase anti-peroxidase for P53 protein, and Feulgen staining for DNA imaging cytometry to DNA contents and S-phase [DNA synthesis of cycling cells were evaluated. The out-come results revealed that P53 and S-phase fraction and DNA content must be in mind when dealing with a human cutaneous leishmaniasis. Consequently, the early detection of any nuclear mutation and cellular proliferation in the skin leishmaniasis lesion[s] must be taken into consideration to avoid the miserable formation of the skin cancer
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Pele
/
Imuno-Histoquímica
/
Linfócitos B
/
Linfócitos T
Tipo de estudo:
Estudo de rastreamento
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
J. Egypt. Soc. Parasitol.
Ano de publicação:
2005
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