Efficacy of conventional interferon alpha-2 b plus ribavirin combination in the treatment of chronic hepatitis C naive patients

ABSTRACT

To assess the efficacy of combination therapy of Conventional interferon alpha-2b plus ribavirin in patients of chronic hepatitis C. Records of 65 patients [43 males and 22 females] of chronic hepatitis C treated with combination therapy of interferon alpha-2b plus ribavirin from January 2003 to December 2003 were analyzed for base-line parameters, response rates and any adverse effects.End-treatment response was found in 86.04% male patients and 86.36% female patients. Sustained response was found in 81.39% male patients and 86.36% female patients.The study shows that conventional interferon plus ribavirin combination therapy remains an effective therapy in the treatment of chronic hepatitis C naive patients in our set-up