Seroepidemiology assay of toxoplasmosis in infants who were confined to bed in infants ward of Taleghani hospital during 1379-1380

ABSTRACT

As some of the mortality and morbidity of infants who are less than one year, is related to contamination with Toxoplasma gondii parasite during fetal time, the aim of this survey is to study the prevalence of Toxoplasmosis in infants visiting Taleghani medical center during 1379-1380. In this survey the sera of 106 and 104 newborn infants from 1 day to 1 month who were suspected to congenital Toxoplasmosis and were hospitalized in Infantile ward of Taleghani hospital were evaluated for IgM and IgG specific antibodies with ELISA and IFA techniques, respectively. According to the results of IFA technique, if the 1/100 is the minimum titer for specific Ig M antibody against Toxoplasmosis, 5 infants were positive and if 1/200 is the minimum titer for specific Ig G antibody against Toxoplasmosis, 41 infants were positive. 6 infants had specific Ig M antibody and 38 infants had specific IgG antibody against Toxoplasmosis by ELISA technique. As a whole, 6 infants [5.66%] were positive which were suggested congenital Toxoplasmosis. With deletion of 6 infected infants, the prevalence of chronic Toxoplasmosis between the mother whose infant was confined in Taleghani hospital was 34 percent by IFA and 30.2 percent by ELISA technique