Synthesis and biological evaluation of certain new substituted pyrido [2,3-d] pyrimidin- 4[1H] -one and pyrido [2,3-d] Triazolo [3,4-b] pyrimidine analogs
SPJ-Saudi Pharmaceutical Journal. 2005; 13 (2-3): 65-73
em Inglês
| IMEMR
| ID: emr-75105
ABSTRACT
The synthesis of a new series of Pyrido[2,3-d]-pyrimidine derivatives 8-13 and their corresponding S-methyl analogs 14 = -19 is described. The pyrido[2,3-d] triazolo[3,4-b]pyrimidines 26, 27 are also prepared. The structures of the newly synthesized compounds have been confirmed by elemental analysis, IR, and 1H-NMR spectra. DNA-binding activity of the synthesized compounds was performed
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Benzofuranos
/
Antineoplásicos
Idioma:
Inglês
Revista:
Saudi Pharm. J.
Ano de publicação:
2005
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