Early detection of neurological involvement in Behcet's disease: electrophysiological, study

ABSTRACT

Several studies have been done to characterize the pattern of neurological involvement in Behcet's disease with neurological involvement. Multi modal neurophysiological studies to characterize cases with non-neurological involvement have not been yet done. The work was to study the electroencephalography pattern [EEG] and evoked potentials abnormalities that may help to diagnose sub-clinical neurological involvement inpatient with Behcet's disease. The study included 29 patients with Behcet's disease [18 male and 11 female] with a male to female ratio 32, their mean age was 32.4 years [ranged from /4-48 year] and the duration of the illness ranged from one year to sixteen years [mean 3.76 year]. The patient group was compared with 25 age and sex matched healthy normal control group. Electroencephalography [EEG] was done for the studied patients it was abnormal in 69%., Visual evoked potential [VEP] was done for 22 patients; it was abnormal in 9 [41%] of the cases., Brain stem auditory evoked potential [BAEP] was done for 22 patients, it was abnormal in 5 patients [22.7%]. Somato-sensory evoked potential [SSEP] was done for 18 patients; it was abnormal in 3 patients [16.6%]