Assessment of the healing activity of oral mucosal tissues of irradiated rats receiving vitamin C following a new modality of CO[2] laser therapy

ABSTRACT

Eighty [80] male albino rats were included in this study. The rats were divided into two groups. The first group [40 rats] subjected to scalpel surgery to excise a biopsy about 2 x 2 mm from the lower anterior labial vestibule. The second group [40 rats] received CO[2] laser in the same way at 6 watts in a focused mode with water irrigation. Ten animals from each group were sacrificed at weekly intervals from the date of beginning of surgery for 3 weeks. The biopsies were assessed histopathologically and immunohistochemically. The results were confirmed by the image analysis and statistical analysis. It has been found that CO[2] laser could be considered as an excellent surgical instrument and become an alternative modality in performing many of surgical procedures