Clinical study of lipid profile in diabetic patients

ABSTRACT

To know the incidence of hypertriglyceridaemia, its age and sex distribution and prevalence in NIDDM and IDDM and also to know the relationship between the glycaemic control and degree of hypertriglyceridaemia and incidence of complications of hypertriglyceridaemia in diabetes mellitus. one hundred and twenty patients of well-established diabetes mellitus were included in the study. All patients underwent the following investigations 1. Base line investigations like blood CP with ESR, Blood urea, urine RE, ECG and x-ray chest. 2. Planned investigations These included fasting and 2 hours post pr and ial blood glucose estimation, serum electrolytes, serum creatinine, serum amylase, uric acid, LFT's, TFT's, ETT and abdominal ultrasound to look for liver texture and for any evidence of fatty change; morphology, texture of kidney and pancreas and other abdominal viscera. 3. Total lipid profile which included Total fasting lipids, Total fasting triglycerides, Total fasting cholesterol, HDL cholesterol and LDL cholesterol. The commonest finding was hypertriglyceridaemia both in insulin- and non-insulin dependent diabetic patients. It was more so in non-insulin dependent diabetes mellitus [70%] as compared to insulin-dependent diabetics [30%]. Hypertiglyceridaemia is the most common lipid abnormality in diabetes mellitus, which is more common in NIDDM than IDDM. Early diagnosis, good glycaemic control and dietary modification are usually enough for prevention and treating hypertriglyceridaemia in diabetes mellitus