study of the relationship between myocardial performance index and left ventricular end-diastolic pressure in patients with left ventricular systolic dysfunction

ABSTRACT

Doppler echocardiography is used to evaluate global myocardial performance. An index of myocardial performance [Tei Index] can be of great prognostic value in heart failure. This study was performed to assess the correlation between Tei Index [TI] and left ventricular end diastolic pressure [LVEDP]. The study group consisted of 38 patients. Each patient underwent ventriculographic evaluation [all had EF<%45]. Eighteen patients had LVEDP< 15 [14 males, 4 females, 57 +/- 6 years old] and 20 subjects [15 males, 5 females, 56 +/- 7 years old] had LVEDP>15. Using Doppler echocardiography. TI was determined for all patients and compared. Mean TI value was significantly different between subjects with LVEDP<15 and those with LVEDP > 15 [0.55 +/- 0.18 vs. 0.76 +/- 1 0.19, P<0.001, T 4.1]. In patients with systolic heart failure [EF <% 45], Tei was significantly lower in subjects with LVEDP<15 compared to those with LVEDP>15. Thus, Tei may be useful for noninvasive assessment of LVEDP in heart failure