Fungal keratitis; role of topical miconazole in management

ABSTRACT

Previously no topical antifungal was available and only dermatological preparation like bifonazole [mycospore] and some systemic antifungal were used for treatment of fungal ulcers. Now miconazole is available as topical ophthalmic ointment for the management of fungal ulcer. To Study the efficacy of topical miconazole ophthalmic ointment in the management of fungal keratitis and to know the time period required for complete healing with topical miconazole ophthalmic ointment. Department of Ophthalmology, Nishtar Hospital, Multan. One year [from March 2001 to February 2002]. Sample size 20 patients. According to this study of 20 cases it is apparent that the fungal keratitis occurred most frequently in patients between 20-70 years of age. It is apparent those males who work at different places are more prone to disease. Out of 20 cases, 10 [50%] were farmers by occupation. Trauma with fingernail in 1[5%] patient, trauma with ston e in 2[10%] patients. No specific eye disease was present in 12[60%] cases. Trachoma was present in 4[20%] cases. Blephritis was diagnosed in 2[10%] cases, 2[10%] patients were suffering from chronic illness like chest infection. Fungal keratitis in 12[60%] was not associated with hypopyon, 6[30%] patients were associated with hypopyon and 2[10%] were associated with end-ophthalmitis. The response was good in 12[60%] patients and satisfactory in 3[15%]. Poor response in 3[15%] and there was no response in 2[10%] cases. Miconazole ophthalmic ointment is a good drug for the treatment of fungal keratitis