Predictors of outcome in hyperglycemic crises in Assiut university hospital [prospective study for one year]

ABSTRACT

Ketoacidosis and hyperosmolar hyperglycemia are the two most serious acute metabolic complications of diabetes even if managed properly [Glaser and Kupperman et al., 1997]. The mortality rate in patients with DKA is < 5% in experienced centers. Also the prognosis of it is substantially worsened at extremes of age and in presence of coma and hypotension [Argent AC 2004]. DKA occurs in 5% of patients with type1 diabetes annually, it is seen less frequently in type2 diabetes [Dunger et al., 2004]. The aim of our study was to Detect the hyperglycemic crises in patients admitted in Intermediate Care Unit in Internal Medicine Department in Assiut University Hospital from May 2005 to May 2006. Determine the survival rate [primary end point] and functional outcome [secondary end point] of patients with hyperglycemic crises. Determine the prognostic factors associated with a fatal outcome of those patients. And To assess the possibility of improvement in the management of the potentially fatal acute hyperglycemic complications of diabetes [DKA and HHS]