Systematic tolerance to the conventional and high copper dental amalgam implants

ABSTRACT

Freshly mixed, unset amalgam of four different types have been implanted in rats tibias for the purpose of evaluation of the effect of their corrosive products on some vital organs; the liver the kidney and blood. The animals were sacrificed after taking the blood samples at 1, 2, 4 and 6 week intervals. Liver and kidney function tests were done. The amount of copper and Zinc in the serum were measured using an Atomic Absorption spectrophotometer-. No significant differences were observed between the control group and the other different between the control group and the other different groups; the corrosive products of the different types of amalgam alloys did not affect the liver and kidney functions, the normal concentration of Cupper and Zinc in blood was not altered