[Report 9 cases of adenoid cystic carcinoma of trachea]

ABSTRACT

Primary malignant neoplasm of trachea are very rare and there is limited information about them. Adenoid cystic carcinoma is a slow-growing malignant tracheal tumor and the best method of treatment is surgical resection. This study was conducted for evaluation of patients with adenoid cystic carcinoma of trachea after treatment. In this descriptive study, all patients treated for adenoid cystic carcinoma between 1995 to 2006 in Mashad Ghaem hospital and Tehran Imam Khomeini hospital, were analyzed statistically. Of nine patients, female to male ratio was 2/1,the mean age of patients was [56.3] years, dyspena and stridor were the most common presenting symptoms [88.8%] and CT scan was the best diagnostic imaging method. The most common site of involvement was in lower third of trachea [44.4%]. [77.7%] of patients underwent surgical resection, hospital mortality after tracheal resection occurred in one patient due to complication [14.2%] aspiration pneumonia. During three years follow up just one patient [11.1%] had tumor recurrence and resection with post operative radiotherapy was performed in this cases overall three-year survival was 88.8%. Because of the nature of adenoid cystic carcinoma in trachea, surgical resection is the best method of treatment, but if surgical margin is positive, post operative radiotherapy will be necessary. In patients who are not candidates for resection, radiotherapy can be an effective alternative treatment