Association between Interleukin-5 and Body Mass Index among Iraqi asthmatic patients

ABSTRACT

Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents are the mediators such as lnterleukin-5 [IL-5]. The aim of this study is to demonstrate the association between IL-5 and obesity in asthma development. One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index [BMI]. This study revealed a significant correlation between IL-5 concentration and BMI [P<0.05], particularly among females. There is certain correlation between obesity and asthma accompanied by IL-5