Prevalance of helicobacter pylori in dyspeptic patients at Lyari General Hospital

ABSTRACT

To find out the frequency of Helicobacter Pylori among patients having dyspepsia. Observational, cross sectional study from Jan. 2005 to Oct. 2005. Department of Surgery at Sindh Govt. Lyari General Hospital, Karachi. Patients presenting with dyspepsia, irrespective of age and sex were included in the study. Complete history of all the patiens was taken and thorough examination done. Upper G.I.Endoscopy was performed, biopsies taken and the specimen sent for histopathology. A total number of 63 patients were studied, out of which 31 were males and 32 females, with ages ranging from 12-68 years. Majority of the patients were in the third and fourth decades of life, and presented with upper abdominal pain and retrosternal burning. Other symptoms seen included regurgitation, dyspepsia, water brash, nausea, vomiting and hematemesis in some cases. Histopathology of gastric biopsy showed Helicobacter pylori associated gastritis in 30 [47.62%] patients, while 33 [52.38%] patients had gastritis which was not associated with Helicobacter pylori infection. The incidence of Helicobacter pylori associated gastritis and gastritis not associated with Helicobacter pylori is more or less equal in dyspeptic patients