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Immunoreactivity of proliferating cell nuclear antigen in transitional cell carcinoma of urinary bladder
Biomedica. 2008; 24 (Jan.-Jun.): 46-49
em Inglês | IMEMR | ID: emr-85994
ABSTRACT
This is a descriptive study designed to evaluate Proliferating cell nuclear antigen [PCNA] in transitional cell carcinoma. A total of fifty per urethra resected bladder tumour samples [TUR BT] were collected from Mayo Hospital and Services Hospital, Lahore and processed for H and E and PCNA stain. The grading of tumours were made on H and E stain. While Proliferating cell nuclear antigen labeling index was recorded for each case. The mean PCNA labeling index was significantly higher in grade III when compared with tumours of grade II. [p < 0.001] carcinoma. Similarly mean PCNA labeling index was significantly higher [p < 0.05] in patients having duration of symptoms up to 3 month when compared with the patients having longer duration of symptoms. The mean PCNA labeling index had significantly higher value in high grade tumours as compared to low grade tumours [p < 0.001]. Although determination of PCNA labeling index is costly yet it has significant role in tumour grading
Assuntos
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Fatores de Tempo / Neoplasias da Bexiga Urinária / Carcinoma de Células de Transição / Seguimentos Limite: Humanos Idioma: Inglês Revista: Biomedica Ano de publicação: 2008

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Fatores de Tempo / Neoplasias da Bexiga Urinária / Carcinoma de Células de Transição / Seguimentos Limite: Humanos Idioma: Inglês Revista: Biomedica Ano de publicação: 2008