Unilateral blindness as a presenting symptom of lung cancer treated with erlotinib
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2008; 18 (2): 125-126
em Inglês
| IMEMR
| ID: emr-87568
ABSTRACT
A non-smoker young man presented to the ophthalmologist with loss of vision in his left eye. Clinical work-up revealed metastatic deposits in left retina. Broadened workup also showed metastatic disease in the skull and brain. The search for the primary concluded on the histopathological evidence of Non-Small Cell Lung Carcinoma [NSCLC] in the upper lobe of the left lung. After the diagnosis and ascertaining disease extent, localized radiotherapy to whole skull and retina was given, followed by conventional chemotherapy [Gemcitabine, Carboplatin]. The results of radiation and chemotherapy were not satisfactory, therefore, patient was placed on a new agent [tyrosine kinase inhibitor] Erlotinib [150 mg per day orally in a single dose]. The response was evaluated using clinical and radiological parameters and was found to be satisfactory
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Retina
/
Cegueira
/
Neoplasias da Retina
/
Receptores ErbB
/
Neoplasias Pulmonares
/
Metástase Neoplásica
Tipo de estudo:
Relato de Casos
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
J. Coll. Physicians Surg. Pak.
Ano de publicação:
2008
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