Glucose-6-phosphate dehydrogenase deficiency in a randomly selected sample in Jordan

ABSTRACT

Glucose-6-Phosphate Dehydrogenase [G6PD] is the first enzyme of the pentose phosphate pathway of glucose metabolism. It occurs in the form of a large number of variants which differ from each other. Many population studies have been reported on G6PD deficiency. In this study the range for normal level of G6PD among Jordanians of different ages were identified. Glucos-6-Phosphate dehydrogenase deficiency was detected in 25 subjects among a group of 496 selected Jordanian subjects, who were apparently healthy. In addition, 12 subjects from the same group were considered to be suspected with G6PD deficiency and needs further investigations