Your browser doesn't support javascript.
loading
Exhaled nitric oxide in stable chronic obstructive pulmonary disease
Annals of Thoracic Medicine. 2009; 4 (2): 65-70
em Inglês | IMEMR | ID: emr-90902
ABSTRACT
The objective of the study was to test the hypothesis that fraction of exhaled nitric oxide [FENO] is elevated in nonsmoking subjects with stable chronic obstructive pulmonary disease [COPD] and compare it with the results in patients with asthma and a control population. Cross-sectional study. Pulmonology Clinic at a University Hospital. Twenty five control subjects, 25 steroid naive asthmatics and 14 COPD patients were studied. All the patients were nonsmokers and stable at the time of the study. All subjects completed a questionnaire and underwent spirometry. Exhaled nitric oxide was measured online by chemiluminescence, using single-breath technique. All the study subjects were males. Subjects with stable COPD had significantly higher values of FENO than controls [56.54 +/- 28.01 vs 22.00 +/- 6.69; P =0.0001] but lower than the subjects with asthma [56.54 +/- 28.01 vs 84.78 +/- 39.32 P = 0.0285].The FENO values in COPD subjects were inversely related to the FEV[1]/FVC ratio. There was a significant overlap between the FENO values in COPD and the control subjects. There is a significant elevation in FENO in patients with stable COPD, but the elevation is less than in asthmatic subjects. Its value in clinical practice may be limited by the significant overlap with control

subjects:

Assuntos
Buscar no Google
Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Asma / Espirometria / Estudos Transversais / Inquéritos e Questionários / Óxido Nítrico Tipo de estudo: Estudo de prevalência Limite: Humanos / Masculino Idioma: Inglês Revista: Ann. Thorac. Med. Ano de publicação: 2009

Similares

MEDLINE

...
LILACS

LIS

Buscar no Google
Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Asma / Espirometria / Estudos Transversais / Inquéritos e Questionários / Óxido Nítrico Tipo de estudo: Estudo de prevalência Limite: Humanos / Masculino Idioma: Inglês Revista: Ann. Thorac. Med. Ano de publicação: 2009