Human papillomavirus infection is principally found with cervical intra-epithelial neoplasia-III in Toluca, State of Mexico

ABSTRACT

To describe the prevalence of human papillomavirus infection [HPV] in cases of cervical intra-epithelial neoplasia [CIN], micro-invasive carcinoma and invasive carcinoma in Toluca, State of Mexico. Cross-sectional study analysing slides with the diagnosis of CIN I to invasive carcinoma for one year and reporting the presence of HPV; also identifying these cervical-uterine cancer stages noted during one semester in the registery of histopathological studies, at the Department of Pathology, General Regional Hospital 220, Instituto Mexicano del Seguro Social [IMSS]. In one year, from a total of 5755 studies, 731 [13%] were of cervical-uterine cancer, 112 [16%] of these were positive for some stage of cervical cancer and 46.43% had HPV infection. In one semester, 2918 histopathological studies were done, 341 [11.68%] of these were cervix uterine biopsies, colposcopies and hysterectomies. 62 women [18.18%] diagnosed with CIN II-III, carcinoma in situ [CIS], micro-invasive carcinoma or invasive carcinoma and finding HPV infection in 51.92% of total cases. The prevalence of HPV was higher than that reported in developed world and CIN II-III are the most common stages in Toluca, State of Mexico