Van Der Woude syndrome: a rare case in Pakistan

ABSTRACT

Congenital epithelial anomalies of the face [sinus of fistula or pits] are uncommon. Most of them involve the lower lip as a part of Van der Woude syndrome. This syndrome presents as a pair of pits in the lower lip vermilion in association with left lip and palate. The incidence is 0.001% of the general population. Additional clinical features include enamel hypoplasia, multiple congenitally missing teeth and abnormality of right limb as a birth defect. Management of the patients involves the collaboration of different specialists. An earlier management of these cases could improve self-esteem and quality of life of the patient. Very few cases of this condition have been reported worldwide. By reporting such new cases we wish to contribute to the understanding of the etiology and to the better knowledge of the details of this very rare condition