Soft-tissue recurrence of giant cell tumor of bone: a case report

ABSTRACT

We report a rare complication of giant cell tumor [GCT] of bone. A soft tissue recurrence without intra-osseous involvement developed in a 35-year-old lady treated for grade III GCT with intralesional excision, local adjuvant phenol and filling the cavity with bone cement. The different imaging modalities used for work-up and staging are discussed. This report emphasizes that a soft tissue recurrence may be not recognized if a thorough clinical examination is not performed and MRI is not done. Review of relevant literature addressed different factors that influence recurrence, as well as the role of osteoinductive growth factors in stimulating the osteoblastic differentiation and metaplastic bone formation in such lesions