Local recurrences of meningeal solitary fibrous tumour with loss of CD34 expression: a diagnostic challenge with prognostic relevance during a 9-year follow-up and literature review

ABSTRACT

We report the case of a 41-year-old man suffering for nine years from solitary fibrous tumour [SFT] of the tentorium cerebella. The tumour recurred twice, being characterized by a stepwise loss of antigenic profile and an enhanced proliferative activity. Meningeal SFTs are seldom described in literature. Malignant variants occur at peripheral sites but are not known within the central nervous system. Our case can provide deeper information about the tumour's behavior during long-term follow-up