Proton magnetic resonance technique in determination of miquitazine

ABSTRACT

A new quantitative method for the determination of Mequitazine and its tablet form [primalan] [R] has been developed. The new method is based on comparison between the integral value of the doublet signal of the protons of the N-methylene at 10-position in Mequitazine and that singlet signal of the hexamine protons at 4.65 ppm. The new method is valuable for both powder and tablet forms, since it gives accurate and reproducible results: