Bulletin of Faculty of Pharmacy-Cairo University. 1993; 31 (1): 107-111
em Inglês
| IMEMR
| ID: emr-95512
ABSTRACT
The lupin alkaloids, [+]-epilupinine N-oxide [2] isolate from Lupinus hirsutus Linn. seeds and [-]-N-methylcytisine [4] from sophora secundiflora Ort. seeds displayed a marked hypoglycaemic effect when administered by intraperitoneal injection to streptozotocin [STZ] induced diabetic mice. [+]-Epilupinine N-oxide [2] was prepared from [+]-epilupinine [1] by chemical semisynthesis. The hypoglycaemic effect was compared with that of Metaformin hydrochloride
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Hipoglicemiantes
Limite:
Animais
Idioma:
Inglês
Revista:
Bull. Fac. Pharm.-Cairo Univ.
Ano de publicação:
1993
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