Carcinosarcoma of the pleura and lung metastasized from a poorly differentiated squamous cell carcinoma of the esophagus
Hematology, Oncology and Stem Cell Therapy. 2010; 3 (1): 47-50
em Inglês
| IMEMR
| ID: emr-98296
ABSTRACT
Transformation of a poorly differentiated squamous cell carcinoma [SCC] of the esophagus into a [carcinosarcoma] of the pleura and lung has never been reported and its histogenetic origin is still debated. A 48-year-old man was admitted due to progressive dysphagia and a weight loss of 5 kilograms within 2 months. Upper gastrointestinal panendoscopic biopsy revealed poorly differentiated SCC of thoracic esophagus, upper third, T4N1M1 a, stage IVa. He received concurrent chemoradiotherapy [CCRT]. About 9 months later, rapid progression of lung metastases and pleural effusion were found. According to the histopathological and immunohistochemical stain results, carcinosarcoma was diagnosed. Palliative therapy was given and the patient eventually died of the disease 9 months after SCC of the thoracic esophagus was diagnosed and one month after carcinosarcoma of the pleura and lung were confirmed
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Neoplasias Pleurais
/
Carcinoma de Células Escamosas
/
Carcinossarcoma
/
Neoplasias Pulmonares
/
Metástase Neoplásica
Tipo de estudo:
Relato de Casos
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Hematol. Oncol. Stem Cell Ther.
Ano de publicação:
2010
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