Dietary fiber psyllium based hydrogels for use in insulin delivery
International Journal of Diabetes Mellitus. 2010; 2 (1): 32-37
em Inglês
| IMEMR
| ID: emr-98500
ABSTRACT
The present article is related to the development of psyllium based oral insulin delivery systems that could release insulin in a controlled and sustained manner. Psyllium is a medicinally important gel, forming glucoe lowering dietary fiber and drug delivery system developed by its functionalization will have the double potential of curing diabetes. Psyllium and acrylamide/methacrylamide based hydrogels were prepared, and the effect of pH on the release dynamics of insulin from drug loaded hydrogels has been studied to evaluate the drug release mechanism. Non-Fickian diffusion mechanism has been observed for the release of insulin in the pH 7.4 buffer
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Hidrogéis
/
Insulina
Idioma:
Inglês
Revista:
Int. J. Diabetes Mellitus
Ano de publicação:
2010
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