Resultats therapeutiques des leucemies aigues lymphoblastiques de l'enfant en Tunisie [181 cas]

ABSTRACT

Average lifetime of childhood acute lymphoblastic leukemia [A.L.L.] has increased considerably during the last decade. Most authors agree to report a recovery rate close to 50%. A retrospective study of 181 patients followed and treated in Tunisia, shows that we are, unfortunately, far from these recovery rates, given that we only obtain a 15% rate of longer than two years survival. Our bad therapeutic results are very probably related to the clinic, cytologic and immunologic profile, characteristic of the A.L.L. in Tunisia. In fact, our series differs from other countries' series by the high percentage of those forms said right away of bad pronostic. For these very high risk forms, a heavy chemotherapy treatment, assisted by an effective hematologic reanimation, should increase the percentage of long survivals