Actividad hemolítica de venenos de serpientes de los géneros Bothrops, Lachesis, Crotalus y Micrurus (Serpentes: Viperidae y Elapidae) / Haemolytic activity of venoms from snakes of the genera Bothrop, Lachesis, Crotalus and Micrurus (Serpentes: Viperidae and Elapidae)
Rev. biol. trop
;
39(2): 311-4, nov. 1991. tab
Artigo
em Espanhol
| LILACS
| ID: lil-113681
ABSTRACT
Hemolytic activity of eight Peruvian snake venoms from the families Viperidae and Elapidae (Bothrops atrox, B. pictus, B. hyoprorus, B. bilineatus, B. neuwedii, Lachesis m. muta, Crotalus d. terrificus, Microrus tschudi), and three Brazilian viperids (B. jararacussu, B. alternatus and C. d. collilineatus) is described. None of the venoms cause direct lysis on washed human erythrocytes. However, all of then caused indirect hemolysis provided that the incubation medium contains an exogenous source of lecithin. Venom of Micrurus tschudi was the most hemolytic (HD50 2.8 ug/ml) while that of B. bilineatus was the least (HD50 681.3 ug/ml). Only six of eleven venoms showed parallel curves of hemolytic activity, and the HD50 varied from 198 to 681 ug/ml and the following decreasing order of hemolytic activity was obtained: L. muta, C. d. terrificus, C. d. collilineatus, B. hyoprorus, B. bilineatus, B. alternatus
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Índice:
LILACS (Américas)
Assunto principal:
Venenos de Víboras
/
Venenos Elapídicos
/
Hemólise
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
/
Humanos
Idioma:
Espanhol
Revista:
Rev. biol. trop
Assunto da revista:
Biologia
/
Medicina Tropical
Ano de publicação:
1991
Tipo de documento:
Artigo
/
Documento de projeto
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