Detection of estrogen receptor in formalin-fixed and paraffin-embedded breast carcinoma: correlation with histological patterns
Rev. paul. med
;
110(4): 158-62, Jul.-Aug. 1992. tab
Artigo
em Inglês
| LILACS
| ID: lil-134387
RESUMO
The authors studied the expression of estrogen receptor (ER) in tissues of breast carcinomas which were previously fixed in formalin and paraffin-embedded. The ER expression was correlated with several histological findings, namely grade of differentiation, tumor necrosis, desmoplasia, lymphocytic infiltration and elastosis. The ER was detected in tissues using the avidin-biotin immunoperoxidase technique associated with the H222 monoclonal antibody from Abbott. All 39 biopsies were of infiltrating ductal carcinoma of breast and 16 of them expressed ER. The statistical analysis showed that the expression of ER was correlated with histological findings of good prognosis as well differentiated carcinomas, no tumor necrosis, absence or mild lymphocytic infiltration around the tumor cells and severe elastosis
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Índice:
LILACS (Américas)
Assunto principal:
Neoplasias da Mama
/
Receptores de Estrogênio
/
Carcinoma Ductal de Mama
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Rev. paul. med
Assunto da revista:
Medicina
Ano de publicação:
1992
Tipo de documento:
Artigo
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