Stool examination and rectal biopsy in the diagnosis and evaluation of therapy of schistosomiasis mansoni
Rev. Inst. Med. Trop. Säo Paulo
;
34(6): 601-8, nov.-dez. 1992. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-134566
ABSTRACT
From each of a group of 217 adult males selected through enzyme-immunoassay or skin-test (Group A), six stool samples were examined by both the Lutz/Hoffman, Pons & Janer (Lutz/HPJ) and Kato/Katz methods. In addition, one oogram of the rectal mucosa was performed. By these methods, schistosomiasis was detected in 44.7%, 47.5% and 40.1% of the individuals respectively. To evaluate the methods in the assessment of cure, the last 40 patients from group A, treated with a single oral dose of oxamniquine at 15 mg/kg were followed up for six months (Group B). The criteria for parasitological cure included three stool examinations by Kato/Katz and Lutz/HPJ methods, one, three and six months post-treatment and a rectal biopsy between the fourth and sixth months post-treatment. The examinations were negative in 87.5%, 90% and 95% of the patients, respectively. The efficacy of oxamniquine was 82.5% when the three methods were considered together and there was no statistically significant difference between the sensitivity of the individual methods:
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Reto
/
Schistosoma mansoni
/
Esquistossomose mansoni
/
Fezes
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Assunto da revista:
Medicina Tropical
Ano de publicação:
1992
Tipo de documento:
Artigo
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