Characterisation of phosphoprotein complexes associated with rat thymocyte Thy-1
Braz. j. med. biol. res
;
27(2): 269-73, Feb. 1994. ilus
Artigo
em Inglês
| LILACS
| ID: lil-140263
ABSTRACT
We have previously demonstrated the non-covalent association of the protein tyrosine kinases p56lck and p60fyn together with a number of substrates for phosphorylation with rat thymocyte Thy-1. Here we present evidence that one of these associated phosphoproteins, p85, is associated by disulphide bridging with another polypeptide, demonstrating that it is an integral membrane protein with an extracellular domain. We also show that phosphatidylinositol 3 kinase activity may be coprecipitated with Thy-1 in Brij 96 thymocyte lysates
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Índice:
LILACS (Américas)
Assunto principal:
Fosfatidilinositóis
/
Fosfoproteínas
/
Proteínas Tirosina Quinases
/
Glicoproteínas de Membrana
/
Glicolipídeos
/
Linfócitos T
Tipo de estudo:
Fatores de risco
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1994
Tipo de documento:
Artigo
/
Congresso e conferência
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