Cytomegalovirus, human herpesvirus 6 and human T cell leukemia virus infection in renal transplanted patients in the northeast of Brazil
Braz. j. med. biol. res
;
26(7): 735-9, Jul. 1993. tab
Artigo
em Inglês
| LILACS
| ID: lil-148727
ABSTRACT
The seroprevalence of antibodies against cytomegalovirus (CMV), human herpesvirus 6 (HHV-6) and human T cell leukemia virus type 1 (HTLV-1), determined by ELISA and by fluorescence in 54 renal transplanted patients, was 96.2 per cent , 88.8 per cent and 11.1 per cent , respectively. These values are relatively high when compared with the results obtained for healthy individuals of the same age groups from Recife, Northeastern Brazil. Active CMV infection was detected by the presence of IgM antibodies and/or virus isolation in 13 (24 per cent ) patients. Kidney rejection and renal dysfunction were observed in 11 of these 13 patients, whereas 3 of 6 HTLV-1 antibody-positive individuals presented these complications. All HTLV-1 positive patients were also positive to IgG CMV and HHV-6 antibodies. The importance of the three viruses in this clinical condition is suggested by the high seropositivity rates compared with the healthy population. The group may also represent a potential source of HTLV-1 infection in this non-endemic area
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Índice:
LILACS (Américas)
Assunto principal:
Infecções por HTLV-I
/
Transplante de Rim
/
Herpesvirus Humano 6
/
Infecções por Citomegalovirus
/
Infecções por Herpesviridae
Tipo de estudo:
Estudo de prevalência
/
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1993
Tipo de documento:
Artigo
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